Clotrimazole Topical

What is clotrimazole topical?

Clotrimazole topical is an antifungal used in the treatment of surface skin infections caused by fungal organisms in cats, dogs, rabbits, birds, reptiles, and other animals. It may be specially compounded and/or combined into a formulation with other medications.

Its use may be off label (extra label) depending on the product formulation, condition(s) being treated, and species being treated. Many drugs are commonly prescribed for off-label use in veterinary medicine. “Off label” means the drug is being used in a way that has not been reviewed or approved by the U.S. Food and Drug Administration (FDA) or Health Canada. In these instances, follow your veterinarian’s directions and cautions very carefully, as their directions may be significantly different from those on the label.

How do I give my pet clotrimazole topical?

• Clotrimazole topical comes in liquid drop, ointment, and spray forms. 
• All forms are applied topically, directly to the skin. 
• Clean the affected area as directed by your veterinarian before applying the medication. 
• Do not let your pet scratch or groom the affected areas for at least 30 minutes after applying.
• Wear gloves and wash your hands after application.
• Avoid contact with eyes.
• Give this medication to your pet for the entire time prescribed by your veterinarian, even if it appears that your pet is feeling better.

This medication should take effect within a few days; however, effects may not be noted outwardly for 1–2 weeks.

What if I miss giving my pet the medication?

If you miss a dose, give it as soon as you remember, and then continue with the regular dosing schedule. However, if it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not give the pet two doses at once.

Are there any potential side effects from clotrimazole topical?

Clotrimazole topical may cause the following side effects:

• Redness, itching, and/or irritation at site of application
• Head shaking or head tilt if applied in or around the external ear canal

The following reactions are rare, but if they occur, contact your veterinarian immediately:

• An allergic reaction such as irregular breathing, rash, fever, puffiness and swelling around the face

Drug sensitivities can develop over time with repeated exposure. Your pet may have no reaction after the first few doses, but may develop a sensitivity later. It is important to watch for signs of an allergic reaction over the entire course of treatment.

Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately. This moderate-acting medication should stop working within a few days.

Are there any risk factors for this medication?

Clotrimazole topical should NOT BE USED in animals who: 

• Are allergic to any of the components or any azole antifungal

Clotrimazole topical should be USED WITH CAUTION in animals who:

• Are pregnant or breeding
• Have liver disease

Are there any drug interactions I should be aware of?

No known drug interactions have been reported for topical preparations of clotrimazole. Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking before starting any new treatment.

Is any monitoring needed with this medication?

• Your veterinarian may schedule a follow-up visit after the course of medication is complete to ensure the infection has been cleared and/or do additional testing to ensure this is the right medication for the type of infection that is present. In this case, follow your veterinarian’s directions.
• At home, monitor for any abnormal changes. If any occur, discontinue the medication and contact your veterinarian.

How do I store clotrimazole topical?

• Store the medication in its original container, protected from light, at room temperature. 
• Keep the cap tightly closed.
• If your veterinarian or pharmacist has made a special (compounded) formulation for your pet, follow the storage recommendations and expiration date for the product.
• Keep medication out of reach of children and pets.

What should I do in case of emergency?

If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility. Adverse effects should also be reported to the FDA or Health Canada.